Cargando…

Aspergillus nidulans Cell Wall Composition and Function Change in Response to Hosting Several Aspergillus fumigatus UDP-Galactopyranose Mutase Activity Mutants

Deletion or repression of Aspergillus nidulans ugmA (AnugmA), involved in galactofuranose biosynthesis, impairs growth and increases sensitivity to Caspofungin, a β-1,3-glucan synthesis antagonist. The A. fumigatus UgmA (AfUgmA) crystal structure has been determined. From that study, AfUgmA mutants...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alam, Md Kausar, van Straaten, Karin E., Sanders, David A. R., Kaminskyj, Susan G. W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893270/ https://www.ncbi.nlm.nih.gov/pubmed/24454924 http://dx.doi.org/10.1371/journal.pone.0085735

Ejemplares similares

Identification of Aspergillus fumigatus UDP-Galactopyranose Mutase Inhibitors
por: Martin del Campo, Julia S., et al.
Publicado: (2017)

Author Correction: Identification of Aspergillus fumigatus UDP-Galactopyranose Mutase Inhibitors
por: Martin del Campo, Julia S., et al.
Publicado: (2018)

Structural Insight into the Unique Substrate Binding Mechanism and Flavin Redox State of UDP-galactopyranose Mutase from Aspergillus fumigatus
por: van Straaten, Karin E., et al.
Publicado: (2012)

Fluorescence Polarization Binding Assay for Aspergillus fumigatus Virulence Factor UDP-Galactopyranose Mutase
por: Qi, Jun, et al.
Publicado: (2011)

Purification, crystallization and preliminary X-ray diffraction data of UDP-galactopyranose mutase from Aspergillus fumigatus
por: Penman, George A., et al.
Publicado: (2012)

Elucidation of Substrate Specificity in Aspergillus nidulans UDP-Galactose-4-Epimerase
por: Dalrymple, Sean A., et al.
Publicado: (2013)

Targeting UDP-Galactopyranose Mutases from Eukaryotic Human Pathogens
por: Kizjakina, Karina, et al.
Publicado: (2013)

In Crystallo Capture of a Covalent Intermediate in the UDP-Galactopyranose Mutase Reaction
por: Mehra-Chaudhary, Ritcha, et al.
Publicado: (2016)

QM/MM Molecular Dynamics Study of the Galactopyranose → Galactofuranose Reaction Catalysed by Trypanosoma cruzi UDP-Galactopyranose Mutase
por: Pierdominici-Sottile, Gustavo, et al.
Publicado: (2014)

Regulation of Development in Aspergillus nidulans and Aspergillus fumigatus
por: Yu, Jae-Hyuk
Publicado: (2010)

UDP-4-Keto-6-Deoxyglucose, a Transient Antifungal Metabolite, Weakens the Fungal Cell Wall Partly by Inhibition of UDP-Galactopyranose Mutase
por: Ma, Liang, et al.
Publicado: (2017)

Cynaroside inhibits Leishmania donovani UDP-galactopyranose mutase and induces reactive oxygen species to exert antileishmanial response
por: Tabrez, Shams, et al.
Publicado: (2021)

Contributions of Unique Active Site Residues of Eukaryotic UDP-Galactopyranose Mutases to Substrate Recognition and Active Site Dynamics
por: Da Fonseca, Isabel, et al.
Publicado: (2014)

Chemical Mechanism of UDP-Galactopyranose Mutase from Trypanosoma cruzi: A Potential Drug Target against Chagas' Disease
por: Oppenheimer, Michelle, et al.
Publicado: (2012)

Genetic and structural validation of Aspergillus fumigatus N-acetylphosphoglucosamine mutase as an antifungal target
por: Fang, Wenxia, et al.
Publicado: (2013)

Pyrazole and Triazole Derivatives as Mycobacterium tuberculosis UDP-Galactopyranose Inhibitors
por: Ahmed, Dalia M., et al.
Publicado: (2022)

A Simple CRISPR/Cas9 System for Efficiently Targeting Genes of Aspergillus Section Flavi Species, Aspergillus nidulans, Aspergillus fumigatus, Aspergillus terreus, and Aspergillus niger
por: Chang, Perng-Kuang
Publicado: (2023)

RNA interference mediated knockdown of Brugia malayi UDP-Galactopyranose mutase severely affects parasite viability, embryogenesis and in vivo development of infective larvae
por: Misra, Sweta, et al.
Publicado: (2017)

Gβ-Like CpcB Plays a Crucial Role for Growth and Development of Aspergillus nidulans and Aspergillus fumigatus
por: Kong, Qing, et al.
Publicado: (2013)

Functional characterization of genes encoding cadmium pumping P(1B)-type ATPases in Aspergillus fumigatus and Aspergillus nidulans
por: Vig, Ildikó, et al.
Publicado: (2023)

Putative cell wall integrity sensor proteins in Aspergillus nidulans
por: Futagami, Taiki, et al.
Publicado: (2012)

Aspergillus nidulans Septa Are Indispensable for Surviving Cell Wall Stress
por: Spence, Ryland N., et al.
Publicado: (2022)

Aspergillus fumigatus—Host Interactions Mediating Airway Wall Remodelling in Asthma
por: Namvar, Sara, et al.
Publicado: (2022)

The Claudin Family Protein FigA Mediates Ca(2+) Homeostasis in Response to Extracellular Stimuli in Aspergillus nidulans and Aspergillus fumigatus
por: Qian, Hui, et al.
Publicado: (2018)

Presence of histones in Aspergillus nidulans
Publicado: (1976)

An Amylase-Like Protein, AmyD, Is the Major Negative Regulator for α-Glucan Synthesis in Aspergillus nidulans during the Asexual Life Cycle
por: He, Xiaoxiao, et al.
Publicado: (2017)

Genetic and structural validation of Aspergillus fumigatus UDP-N-acetylglucosamine pyrophosphorylase as an antifungal target
por: Fang, Wenxia, et al.
Publicado: (2013)

Analysis of mitotic nondisjunction with Aspergillus nidulans.
por: Morpurgo, G, et al.
Publicado: (1979)

Functional Analysis of the Aspergillus nidulans Kinome
por: De Souza, Colin P., et al.
Publicado: (2013)

Genetics of Polyketide Metabolism in Aspergillus nidulans
por: Klejnstrup, Marie L., et al.
Publicado: (2012)

Identification of Glucose Transporters in Aspergillus nidulans
por: dos Reis, Thaila Fernanda, et al.
Publicado: (2013)

CARS spectroscopy of Aspergillus nidulans spores
por: D. Strycker, Benjamin, et al.
Publicado: (2019)

Aspergillus fumigatus in Poultry
por: Arné, Pascal, et al.
Publicado: (2011)

Cytological characterization of an Aspergillus Nidulans mutant from a strain with chromosomic duplication
por: Giancoli, Ágata Cristiane Huppert, et al.
Publicado: (2010)

Dynamic Transcriptomic and Phosphoproteomic Analysis During Cell Wall Stress in Aspergillus nidulans
por: Chelius, Cynthia, et al.
Publicado: (2020)

A heterologous expression platform in Aspergillus nidulans for the elucidation of cryptic secondary metabolism biosynthetic gene clusters: discovery of the Aspergillus fumigatus sartorypyrone biosynthetic pathway
por: Lin, Shu-Yi, et al.
Publicado: (2023)

Toxic metal tolerance of Aspergillus flavus and Aspergillus nidulans isolated from tailings
por: Villalba-Villalba, Ana G., et al.
Publicado: (2023)

Colistin and Isavuconazole Interact Synergistically In Vitro against Aspergillus nidulans and Aspergillus niger
por: Schwarz, Patrick, et al.
Publicado: (2020)

Aspergillus fumigatus Fumagillin Contributes to Host Cell Damage
por: Guruceaga, Xabier, et al.
Publicado: (2021)

N-Myristoyltransferase Is a Cell Wall Target in Aspergillus fumigatus
por: Fang, Wenxia, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_8tspnp2foduh516h0b8so5pieu