Sodium-Coupled Neutral Amino Acid Transporter 1 (SNAT1) Modulates L-Citrulline Transport and Nitric Oxide (NO) Signaling in Piglet Pulmonary Arterial Endothelial Cells

RATIONALE: There is evidence that impairments in nitric oxide (NO) signaling contribute to chronic hypoxia-induced pulmonary hypertension. The L-arginine-NO precursor, L-citrulline, has been shown to ameliorate pulmonary hypertension. Sodium-coupled neutral amino acid transporters (SNATs) are involv...

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Detalles Bibliográficos
Autores principales: Dikalova, Anna, Fagiana, Angela, Aschner, Judy L., Aschner, Michael, Summar, Marshall, Fike, Candice D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893279/
https://www.ncbi.nlm.nih.gov/pubmed/24454923
http://dx.doi.org/10.1371/journal.pone.0085730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893279/
https://www.ncbi.nlm.nih.gov/pubmed/24454923
http://dx.doi.org/10.1371/journal.pone.0085730

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