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Sodium-Coupled Neutral Amino Acid Transporter 1 (SNAT1) Modulates L-Citrulline Transport and Nitric Oxide (NO) Signaling in Piglet Pulmonary Arterial Endothelial Cells

RATIONALE: There is evidence that impairments in nitric oxide (NO) signaling contribute to chronic hypoxia-induced pulmonary hypertension. The L-arginine-NO precursor, L-citrulline, has been shown to ameliorate pulmonary hypertension. Sodium-coupled neutral amino acid transporters (SNATs) are involv...

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Detalles Bibliográficos
Autores principales:	Dikalova, Anna, Fagiana, Angela, Aschner, Judy L., Aschner, Michael, Summar, Marshall, Fike, Candice D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893279/ https://www.ncbi.nlm.nih.gov/pubmed/24454923 http://dx.doi.org/10.1371/journal.pone.0085730

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