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Drug Targets for Cell Cycle Dysregulators in Leukemogenesis: In Silico Docking Studies

Alterations in cell cycle regulating proteins are a key characteristic in neoplastic proliferation of lymphoblast cells in patients with Acute Lymphoblastic Leukemia (ALL). The aim of our study was to investigate whether the routinely administered ALL chemotherapeutic agents would be able to bind an...

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Detalles Bibliográficos
Autores principales: Jayaraman, Archana, Jamil, Kaiser
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893288/
https://www.ncbi.nlm.nih.gov/pubmed/24454966
http://dx.doi.org/10.1371/journal.pone.0086310