Characterization of Angiotensin-Converting Enzyme 2 Ectodomain Shedding from Mouse Proximal Tubular Cells

Angiotensin-converting enzyme 2 (ACE2) is highly expressed in the kidney proximal tubule, where it cleaves angiotensin (Ang) II to Ang-(1-7). Urinary ACE2 levels increase in diabetes, suggesting that ACE2 may be shed from tubular cells. The aim of this study was to determine if ACE2 is shed from pro...

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Detalles Bibliográficos
Autores principales: Xiao, Fengxia, Zimpelmann, Joseph, Agaybi, Samih, Gurley, Susan B., Puente, Lawrence, Burns, Kevin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893316/
https://www.ncbi.nlm.nih.gov/pubmed/24454948
http://dx.doi.org/10.1371/journal.pone.0085958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893316/
https://www.ncbi.nlm.nih.gov/pubmed/24454948
http://dx.doi.org/10.1371/journal.pone.0085958

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