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Tau pathology induces loss of GABAergic interneurons leading to altered synaptic plasticity and behavioral impairments
BACKGROUND: Tau is a microtubule stabilizing protein and is mainly expressed in neurons. Tau aggregation into oligomers and tangles is considered an important pathological event in tauopathies, such as frontotemporal dementia (FTD) and Alzheimer’s disease (AD). Tauopathies are also associated with d...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893396/ https://www.ncbi.nlm.nih.gov/pubmed/24252661 http://dx.doi.org/10.1186/2051-5960-1-34 |