Myelin alters the inflammatory phenotype of macrophages by activating PPARs

BACKGROUND: Foamy macrophages, containing myelin degradation products, are abundantly found in active multiple sclerosis (MS) lesions. Recent studies have described an altered phenotype of macrophages after myelin internalization. However, mechanisms by which myelin affects the phenotype of macropha...

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Detalles Bibliográficos
Autores principales: Bogie, Jeroen FJ, Jorissen, Winde, Mailleux, Jo, Nijland, Philip G, Zelcer, Noam, Vanmierlo, Tim, Van Horssen, Jack, Stinissen, Piet, Hellings, Niels, Hendriks, Jerome JA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893408/
https://www.ncbi.nlm.nih.gov/pubmed/24252308
http://dx.doi.org/10.1186/2051-5960-1-43

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893408/
https://www.ncbi.nlm.nih.gov/pubmed/24252308
http://dx.doi.org/10.1186/2051-5960-1-43

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