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The link between intraneuronal N-truncated amyloid-β peptide and oxidatively modified lipids in idiopathic autism and dup(15q11.2-q13)/autism

BACKGROUND: Autism is a neurodevelopmental disorder of unknown etiopathogenesis associated with structural and functional abnormalities of neurons and increased formation of reactive oxygen species. Our previous study revealed enhanced accumulation of amino-terminally truncated amyloid-β (Aβ) in bra...

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Detalles Bibliográficos
Autores principales: Frackowiak, Janusz, Mazur-Kolecka, Bozena, Schanen, N Carolyn, Brown, W Ted, Wegiel, Jerzy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893450/
https://www.ncbi.nlm.nih.gov/pubmed/24252310
http://dx.doi.org/10.1186/2051-5960-1-61