Telomere shortening correlates to dysplasia but not to DNA aneuploidy in longstanding ulcerative colitis

BACKGROUND: Ulcerative colitis (UC) is a chronic, inflammatory bowel disease which may lead to dysplasia and adenocarcinoma in patients when long-lasting. Short telomeres have been reported in mucosal cells of UC patients. Telomeres are repetitive base sequences capping the ends of linear chromosome...

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Detalles Bibliográficos
Autores principales: Friis-Ottessen, Mariann, Bendix, Laila, Kølvraa, Steen, Norheim-Andersen, Solveig, De Angelis, Paula M, Clausen, Ole Petter F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893461/
https://www.ncbi.nlm.nih.gov/pubmed/24405569
http://dx.doi.org/10.1186/1471-230X-14-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893461/
https://www.ncbi.nlm.nih.gov/pubmed/24405569
http://dx.doi.org/10.1186/1471-230X-14-8

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