Excitotoxin-induced caspase-3 activation and microtubule disintegration in axons is inhibited by taxol

BACKGROUND: Axon degeneration, a key pathological event in many neurodegenerative diseases and injury, can be induced by somatodendritic excitotoxin exposure. It is currently unclear, however, whether excitotoxin-induced axon degeneration is mechanistically similar to Wallerian degeneration, which o...

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Detalles Bibliográficos
Autores principales: King, Anna Elizabeth, Southam, Katherine Adriana, Dittmann, Justin, Vickers, James Clement
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893530/
https://www.ncbi.nlm.nih.gov/pubmed/24252213
http://dx.doi.org/10.1186/2051-5960-1-59

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893530/
https://www.ncbi.nlm.nih.gov/pubmed/24252213
http://dx.doi.org/10.1186/2051-5960-1-59

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