Cargando…
Excitotoxin-induced caspase-3 activation and microtubule disintegration in axons is inhibited by taxol
BACKGROUND: Axon degeneration, a key pathological event in many neurodegenerative diseases and injury, can be induced by somatodendritic excitotoxin exposure. It is currently unclear, however, whether excitotoxin-induced axon degeneration is mechanistically similar to Wallerian degeneration, which o...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893530/ https://www.ncbi.nlm.nih.gov/pubmed/24252213 http://dx.doi.org/10.1186/2051-5960-1-59 |