Unusual cerebral vascular prion protein amyloid distribution in scrapie-infected transgenic mice expressing anchorless prion protein

BACKGROUND: In some prion diseases, misfolded aggregated protease-resistant prion protein (PrPres) is found in brain as amyloid, which can cause cerebral amyloid angiopathy. Small diffusible precursors of PrPres amyloid might flow with brain interstitial fluid (ISF), possibly accounting for the peri...

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Detalles Bibliográficos
Autores principales: Rangel, Alejandra, Race, Brent, Klingeborn, Mikael, Striebel, James, Chesebro, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893542/
https://www.ncbi.nlm.nih.gov/pubmed/24252347
http://dx.doi.org/10.1186/2051-5960-1-25

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893542/
https://www.ncbi.nlm.nih.gov/pubmed/24252347
http://dx.doi.org/10.1186/2051-5960-1-25

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