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Disturbances in the murine hepatic circadian clock in alcohol-induced hepatic steatosis

To investigate the role of the circadian clock in the development of alcohol-induced fatty liver disease we examined livers of mice chronically alcohol-fed over 4-weeks that resulted in steatosis. Here we show time-of-day specific changes in expression of clock genes and clock-controlled genes, incl...

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Detalles Bibliográficos
Autores principales: Zhou, Peng, Ross, Ruth A., Pywell, Cameron M., Liangpunsakul, Suthat, Duffield, Giles E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893658/
https://www.ncbi.nlm.nih.gov/pubmed/24430730
http://dx.doi.org/10.1038/srep03725