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Negative learning bias is associated with risk aversion in a genetic animal model of depression

The lateral habenula (LHb) is activated by aversive stimuli and the omission of reward, inhibited by rewarding stimuli and is hyperactive in helpless rats—an animal model of depression. Here we test the hypothesis that congenital learned helpless (cLH) rats are more sensitive to decreases in reward...

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Detalles Bibliográficos
Autores principales: Shabel, Steven J., Murphy, Ryan T., Malinow, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893716/
https://www.ncbi.nlm.nih.gov/pubmed/24474914
http://dx.doi.org/10.3389/fnhum.2014.00001