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Negative learning bias is associated with risk aversion in a genetic animal model of depression
The lateral habenula (LHb) is activated by aversive stimuli and the omission of reward, inhibited by rewarding stimuli and is hyperactive in helpless rats—an animal model of depression. Here we test the hypothesis that congenital learned helpless (cLH) rats are more sensitive to decreases in reward...
Autores principales: | Shabel, Steven J., Murphy, Ryan T., Malinow, Roberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893716/ https://www.ncbi.nlm.nih.gov/pubmed/24474914 http://dx.doi.org/10.3389/fnhum.2014.00001 |
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