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Involvement of Differential Relationship between HCV Replication and Hepatic PRR Signaling Gene Expression in Responsiveness to IFN-Based Therapy

Aim. To gain an insight into the effect of HCV replication-associated interference with the IFN system on hepatic mRNA expression involved in IFN production. Methods. Relative mRNA expression of TLR3/RIG-I signaling genes involved in IFN-β production was correlated with positive- and negative-strand...

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Detalles Bibliográficos
Autores principales: Yuki, Nobukazu, Matsumoto, Shinji, Kato, Michio, Yamaguchi, Toshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893785/
https://www.ncbi.nlm.nih.gov/pubmed/24490062
http://dx.doi.org/10.1155/2013/917261