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Phosphoproteomics of collagen receptor networks reveals SHP-2 phosphorylation downstream of wild-type DDR2 and its lung cancer mutants

Collagen is an important extracellular matrix component that directs many fundamental cellular processes including differentiation, proliferation and motility. The signalling networks driving these processes are propagated by collagen receptors such as the β1 integrins and the DDRs (discoidin domain...

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Detalles Bibliográficos
Autores principales: Iwai, Leo K., Payne, Leo S., Luczynski, Maciej T., Chang, Francis, Xu, Huifang, Clinton, Ryan W., Paul, Angela, Esposito, Edward A., Gridley, Scott, Leitinger, Birgit, Naegle, Kristen M., Huang, Paul H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893797/
https://www.ncbi.nlm.nih.gov/pubmed/23822953
http://dx.doi.org/10.1042/BJ20121750