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Andrographolide, a Novel NF-κB Inhibitor, Induces Vascular Smooth Muscle Cell Apoptosis via a Ceramide-p47phox-ROS Signaling Cascade

Atherosclerosis is linked with the development of many cardiovascular complications. Abnormal proliferation of vascular smooth muscle cells (VSMCs) plays a crucial role in the development of atherosclerosis. Accordingly, the apoptosis of VSMCs, which occurs in the progression of vascular proliferati...

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Detalles Bibliográficos
Autores principales: Chen, Yu-Ying, Hsu, Ming-Jen, Sheu, Joen-Rong, Lee, Lin-Wen, Hsieh, Cheng-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893871/
https://www.ncbi.nlm.nih.gov/pubmed/24489592
http://dx.doi.org/10.1155/2013/821813