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Glycocalyx Engineering Reveals a Siglec-Based Mechanism for NK Cell Immunoevasion
The increase of cell surface sialic acid is a characteristic shared by many tumor types. A correlation between hypersialylation and immunoprotection has been observed, but few hypotheses have provided a mechanistic understanding of this immunosuppressive phenomenon. Here, we show that increasing sia...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893890/ https://www.ncbi.nlm.nih.gov/pubmed/24292068 http://dx.doi.org/10.1038/nchembio.1388 |