Cargando…

Zinc Finger Transcription Factors Displaced SREBP Proteins as the Major Sterol Regulators during Saccharomycotina Evolution

In most eukaryotes, including the majority of fungi, expression of sterol biosynthesis genes is regulated by Sterol-Regulatory Element Binding Proteins (SREBPs), which are basic helix-loop-helix transcription activators. However, in yeasts such as Saccharomyces cerevisiae and Candida albicans sterol...

Descripción completa

Detalles Bibliográficos
Autores principales: Maguire, Sarah L., Wang, Can, Holland, Linda M., Brunel, François, Neuvéglise, Cécile, Nicaud, Jean-Marc, Zavrel, Martin, White, Theodore C., Wolfe, Kenneth H., Butler, Geraldine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894159/
https://www.ncbi.nlm.nih.gov/pubmed/24453983
http://dx.doi.org/10.1371/journal.pgen.1004076