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Zinc Finger Transcription Factors Displaced SREBP Proteins as the Major Sterol Regulators during Saccharomycotina Evolution
In most eukaryotes, including the majority of fungi, expression of sterol biosynthesis genes is regulated by Sterol-Regulatory Element Binding Proteins (SREBPs), which are basic helix-loop-helix transcription activators. However, in yeasts such as Saccharomyces cerevisiae and Candida albicans sterol...
Autores principales: | Maguire, Sarah L., Wang, Can, Holland, Linda M., Brunel, François, Neuvéglise, Cécile, Nicaud, Jean-Marc, Zavrel, Martin, White, Theodore C., Wolfe, Kenneth H., Butler, Geraldine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894159/ https://www.ncbi.nlm.nih.gov/pubmed/24453983 http://dx.doi.org/10.1371/journal.pgen.1004076 |
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