Coarse-Grained Molecular Simulation of Epidermal Growth Factor Receptor Protein Tyrosine Kinase Multi-Site Self-Phosphorylation

Upon the ligand-dependent dimerization of the epidermal growth factor receptor (EGFR), the intrinsic protein tyrosine kinase (PTK) activity of one receptor monomer is activated, and the dimeric receptor undergoes self-phosphorylation at any of eight candidate phosphorylation sites (P-sites) in eithe...

Descripción completa

Detalles Bibliográficos
Autor principal: Koland, John G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894164/
https://www.ncbi.nlm.nih.gov/pubmed/24453959
http://dx.doi.org/10.1371/journal.pcbi.1003435

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894164/
https://www.ncbi.nlm.nih.gov/pubmed/24453959
http://dx.doi.org/10.1371/journal.pcbi.1003435

Ejemplares similares