Defining NELF-E RNA Binding in HIV-1 and Promoter-Proximal Pause Regions

The four-subunit Negative Elongation Factor (NELF) is a major regulator of RNA Polymerase II (Pol II) pausing. The subunit NELF-E contains a conserved RNA Recognition Motif (RRM) and is proposed to facilitate Poll II pausing through its association with nascent transcribed RNA. However, conflicting...

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Detalles Bibliográficos
Autores principales: Pagano, John M., Kwak, Hojoong, Waters, Colin T., Sprouse, Rebekka O., White, Brian S., Ozer, Abdullah, Szeto, Kylan, Shalloway, David, Craighead, Harold G., Lis, John T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894171/
https://www.ncbi.nlm.nih.gov/pubmed/24453987
http://dx.doi.org/10.1371/journal.pgen.1004090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894171/
https://www.ncbi.nlm.nih.gov/pubmed/24453987
http://dx.doi.org/10.1371/journal.pgen.1004090

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