Cargando…
Defining NELF-E RNA Binding in HIV-1 and Promoter-Proximal Pause Regions
The four-subunit Negative Elongation Factor (NELF) is a major regulator of RNA Polymerase II (Pol II) pausing. The subunit NELF-E contains a conserved RNA Recognition Motif (RRM) and is proposed to facilitate Poll II pausing through its association with nascent transcribed RNA. However, conflicting...
Autores principales: | Pagano, John M., Kwak, Hojoong, Waters, Colin T., Sprouse, Rebekka O., White, Brian S., Ozer, Abdullah, Szeto, Kylan, Shalloway, David, Craighead, Harold G., Lis, John T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894171/ https://www.ncbi.nlm.nih.gov/pubmed/24453987 http://dx.doi.org/10.1371/journal.pgen.1004090 |
Ejemplares similares
-
RAPID-SELEX for RNA Aptamers
por: Szeto, Kylan, et al.
Publicado: (2013) -
Multiplexed
Microcolumn-Based Process for Efficient
Selection of RNA Aptamers
por: Latulippe, David R., et al.
Publicado: (2013) -
The NELF pausing checkpoint mediates the functional divergence of Cdk9
por: DeBerardine, Michael, et al.
Publicado: (2023) -
High-throughput binding characterization of RNA aptamer selections using a microplate-based multiplex microcolumn device
por: Szeto, Kylan, et al.
Publicado: (2014) -
Genome-wide dynamics of Pol II elongation and its interplay with promoter proximal pausing, chromatin, and exons
por: Jonkers, Iris, et al.
Publicado: (2014)