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Increase in TGF-β Secreting CD4(+)CD25(+) FOXP3(+) T Regulatory Cells in Anergic Lepromatous Leprosy Patients
BACKGROUND: Lepromatous leprosy caused by Mycobacterium leprae is associated with antigen specific T cell unresponsiveness/anergy whose underlying mechanisms are not fully defined. We investigated the role of CD25(+)FOXP3(+) regulatory T cells in both skin lesions and M.leprae stimulated PBMC cultur...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894184/ https://www.ncbi.nlm.nih.gov/pubmed/24454972 http://dx.doi.org/10.1371/journal.pntd.0002639 |