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Reversal Effect of ST6GAL 1 on Multidrug Resistance in Human Leukemia by Regulating the PI3K/Akt Pathway and the Expression of P-gp and MRP1

β-galactoside α2, 6-sialyltransferse gene (ST6GAL) family has two members, which encode corresponding enzymes ST6Gal I and ST6Gal II. The present atudy was to investigate whether and how ST6GAL family involved in multidrug resistance (MDR) in human leukemia cell lines and bone marrow mononuclear cel...

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Detalles Bibliográficos
Autores principales: Ma, Hongye, Cheng, Lei, Hao, Keji, Li, Yanping, Song, Xiaobo, Zhou, Huimin, Jia, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894187/
https://www.ncbi.nlm.nih.gov/pubmed/24454800
http://dx.doi.org/10.1371/journal.pone.0085113