Antimicrobial Cathelicidin Peptide LL-37 Inhibits the LPS/ATP-Induced Pyroptosis of Macrophages by Dual Mechanism

Pyroptosis is a caspase-1 dependent cell death, associated with proinflammatory cytokine production, and is considered to play a crucial role in sepsis. Pyroptosis is induced by the two distinct stimuli, microbial PAMPs (pathogen associated molecular patterns) and endogenous DAMPs (damage associated...

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Detalles Bibliográficos
Autores principales: Hu, Zhongshuang, Murakami, Taisuke, Suzuki, Kaori, Tamura, Hiroshi, Kuwahara-Arai, Kyoko, Iba, Toshiaki, Nagaoka, Isao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894207/
https://www.ncbi.nlm.nih.gov/pubmed/24454930
http://dx.doi.org/10.1371/journal.pone.0085765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894207/
https://www.ncbi.nlm.nih.gov/pubmed/24454930
http://dx.doi.org/10.1371/journal.pone.0085765

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