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A Substrate-Fusion Protein Is Trapped inside the Type III Secretion System Channel in Shigella flexneri

The Type III Secretion System (T3SS) is a macromolecular complex used by Gram-negative bacteria to secrete effector proteins from the cytoplasm across the bacterial envelope in a single step. For many pathogens, the T3SS is an essential virulence factor that enables the bacteria to interact with and...

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Detalles Bibliográficos
Autores principales: Dohlich, Kim, Zumsteg, Anna Brotcke, Goosmann, Christian, Kolbe, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894212/
https://www.ncbi.nlm.nih.gov/pubmed/24453973
http://dx.doi.org/10.1371/journal.ppat.1003881