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Glutamate Utilization Couples Oxidative Stress Defense and the Tricarboxylic Acid Cycle in Francisella Phagosomal Escape

Intracellular bacterial pathogens have developed a variety of strategies to avoid degradation by the host innate immune defense mechanisms triggered upon phagocytocis. Upon infection of mammalian host cells, the intracellular pathogen Francisella replicates exclusively in the cytosolic compartment....

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Detalles Bibliográficos
Autores principales: Ramond, Elodie, Gesbert, Gael, Rigard, Mélanie, Dairou, Julien, Dupuis, Marion, Dubail, Iharilalao, Meibom, Karin, Henry, Thomas, Barel, Monique, Charbit, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894225/
https://www.ncbi.nlm.nih.gov/pubmed/24453979
http://dx.doi.org/10.1371/journal.ppat.1003893