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Kinetics of promoter Pol II on Hsp70 reveal stable pausing and key insights into its regulation

The kinetics with which promoter-proximal paused RNA polymerase II (Pol II) undergoes premature termination versus productive elongation is central to understanding underlying mechanisms of metazoan transcription regulation. To assess the fate of Pol II quantitatively, we tracked photoactivatable GF...

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Detalles Bibliográficos
Autores principales: Buckley, Martin S., Kwak, Hojoong, Zipfel, Warren R., Lis, John T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894409/
https://www.ncbi.nlm.nih.gov/pubmed/24395245
http://dx.doi.org/10.1101/gad.231886.113