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Kinetics of promoter Pol II on Hsp70 reveal stable pausing and key insights into its regulation
The kinetics with which promoter-proximal paused RNA polymerase II (Pol II) undergoes premature termination versus productive elongation is central to understanding underlying mechanisms of metazoan transcription regulation. To assess the fate of Pol II quantitatively, we tracked photoactivatable GF...
Autores principales: | Buckley, Martin S., Kwak, Hojoong, Zipfel, Warren R., Lis, John T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894409/ https://www.ncbi.nlm.nih.gov/pubmed/24395245 http://dx.doi.org/10.1101/gad.231886.113 |
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