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Astrocytes engage unique molecular programs to engulf pruned neuronal debris from distinct subsets of neurons

Precise neural circuit assembly is achieved by initial overproduction of neurons and synapses, followed by refinement through elimination of exuberant neurons and synapses. Glial cells are the primary cells responsible for clearing neuronal debris, but the cellular and molecular basis of glial pruni...

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Detalles Bibliográficos
Autores principales: Tasdemir-Yilmaz, Ozge E., Freeman, Marc R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894410/
https://www.ncbi.nlm.nih.gov/pubmed/24361692
http://dx.doi.org/10.1101/gad.229518.113