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Astrocytes engage unique molecular programs to engulf pruned neuronal debris from distinct subsets of neurons
Precise neural circuit assembly is achieved by initial overproduction of neurons and synapses, followed by refinement through elimination of exuberant neurons and synapses. Glial cells are the primary cells responsible for clearing neuronal debris, but the cellular and molecular basis of glial pruni...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894410/ https://www.ncbi.nlm.nih.gov/pubmed/24361692 http://dx.doi.org/10.1101/gad.229518.113 |