CLOCK:BMAL1 is a pioneer-like transcription factor

The mammalian circadian clock relies on the master genes CLOCK and BMAL1 to drive rhythmic gene expression and regulate biological functions under circadian control. Here we show that rhythmic CLOCK:BMAL1 DNA binding promotes rhythmic chromatin opening. Mechanisms include CLOCK:BMAL1 binding to nucl...

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Detalles Bibliográficos
Autores principales: Menet, Jerome S., Pescatore, Stefan, Rosbash, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Research Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894415/
https://www.ncbi.nlm.nih.gov/pubmed/24395244
http://dx.doi.org/10.1101/gad.228536.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894415/
https://www.ncbi.nlm.nih.gov/pubmed/24395244
http://dx.doi.org/10.1101/gad.228536.113

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