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A modular and flexible ESC-based mouse model of pancreatic cancer

Genetically engineered mouse models (GEMMs) have greatly expanded our knowledge of pancreatic ductal adenocarcinoma (PDAC) and serve as a critical tool to identify and evaluate new treatment strategies. However, the cost and time required to generate conventional pancreatic cancer GEMMs limits their...

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Detalles Bibliográficos
Autores principales: Saborowski, Michael, Saborowski, Anna, Morris, John P., Bosbach, Benedikt, Dow, Lukas E., Pelletier, Jerry, Klimstra, David S., Lowe, Scott W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894416/
https://www.ncbi.nlm.nih.gov/pubmed/24395249
http://dx.doi.org/10.1101/gad.232082.113