Identification of a gene for an ancient cytokine, interleukin 15-like, in mammals; interleukins 2 and 15 co-evolved with this third family member, all sharing binding motifs for IL-15Rα

Interleukins 2 and 15 (IL-2 and IL-15) are highly differentiated but related cytokines with overlapping, yet also distinct functions, and established benefits for medical drug use. The present study identified a gene for an ancient third IL-2/15 family member in reptiles and mammals, interleukin 15-...

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Detalles Bibliográficos
Autores principales: Dijkstra, Johannes M., Takizawa, Fumio, Fischer, Uwe, Friedrich, Maik, Soto-Lampe, Veronica, Lefèvre, Christophe, Lenk, Matthias, Karger, Axel, Matsui, Taei, Hashimoto, Keiichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894449/
https://www.ncbi.nlm.nih.gov/pubmed/24276591
http://dx.doi.org/10.1007/s00251-013-0747-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894449/
https://www.ncbi.nlm.nih.gov/pubmed/24276591
http://dx.doi.org/10.1007/s00251-013-0747-0

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