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Modulation of the cardiac sodium/bicarbonate cotransporter by the renin angiotensin aldosterone system: pathophysiological consequences
The sodium/bicarbonate cotransporter (NBC) is one of the major alkalinizing mechanisms in the cardiomyocytes. It has been demonstrated the existence of at least two functional isoforms, one that promotes the co-influx of 1 molecule of Na(+) per 1 molecule of HCO(−)(3) (electroneutral isoform; NBCn1)...
Autores principales: | De Giusti, Verónica C., Ciancio, María C., Orlowski, Alejandro, Aiello, Ernesto A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894460/ https://www.ncbi.nlm.nih.gov/pubmed/24478712 http://dx.doi.org/10.3389/fphys.2013.00411 |
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