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Promoter Targeting shRNA Suppresses HIV-1 Infection In vivo Through Transcriptional Gene Silencing

Despite prolonged and intensive application, combined antiretroviral therapy cannot eradicate human immunodeficiency virus (HIV)-1 because it is harbored as a latent infection, surviving for long periods of time. Alternative approaches are required to overcome the limitations of current therapy. We...

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Detalles Bibliográficos
Autores principales: Suzuki, Kazuo, Hattori, Shinichiro, Marks, Katherine, Ahlenstiel, Chantelle, Maeda, Yosuke, Ishida, Takaomi, Millington, Michelle, Boyd, Maureen, Symonds, Geoff, Cooper, David A, Okada, Seiji, Kelleher, Anthony D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894581/
https://www.ncbi.nlm.nih.gov/pubmed/24301868
http://dx.doi.org/10.1038/mtna.2013.64