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Network Pharmacology Strategies Toward Multi-Target Anticancer Therapies: From Computational Models to Experimental Design Principles

Polypharmacology has emerged as novel means in drug discovery for improving treatment response in clinical use. However, to really capitalize on the polypharmacological effects of drugs, there is a critical need to better model and understand how the complex interactions between drugs and their cell...

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Detalles Bibliográficos
Autores principales: Tang, Jing, Aittokallio, Tero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894695/
https://www.ncbi.nlm.nih.gov/pubmed/23530504
http://dx.doi.org/10.2174/13816128113199990470