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Cytotoxicity and Apoptosis Induced by a Plumbagin Derivative in Estrogen Positive MCF-7 Breast Cancer Cells

Plumbagin [5-hydroxy- 2-methyl-1, 4-naphthaquinone] is a well-known plant derived anticancer lead compound. Several efforts have been made to synthesize its analogs and derivatives in order to increase its anticancer potential. In the present study, plumbagin and its five derivatives have been evalu...

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Detalles Bibliográficos
Autores principales: Sagar, Sunil, Esau, Luke, Moosa, Basem, Khashab, Niveen M., Bajic, Vladimir B., Kaur, Mandeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894702/
https://www.ncbi.nlm.nih.gov/pubmed/24164046
http://dx.doi.org/10.2174/18715206113136660369