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Expression and Functional Characterization of Membrane-Integrated Mammalian Corticotropin Releasing Factor Receptors 1 and 2 in Escherichia coli

Corticotropin-Releasing Factor Receptors (CRFRs) are class B1 G-protein-coupled receptors, which bind peptides of the corticotropin releasing factor family and are key mediators in the stress response. In order to dissect the receptors' binding specificity and enable structural studies, full-le...

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Detalles Bibliográficos
Autores principales: Jappelli, Roberto, Perrin, Marilyn H., Lewis, Kathy A., Vaughan, Joan M., Tzitzilonis, Christos, Rivier, Jean E., Vale, Wylie W., Riek, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894963/
https://www.ncbi.nlm.nih.gov/pubmed/24465390
http://dx.doi.org/10.1371/journal.pone.0084013