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Expression and Functional Characterization of Membrane-Integrated Mammalian Corticotropin Releasing Factor Receptors 1 and 2 in Escherichia coli
Corticotropin-Releasing Factor Receptors (CRFRs) are class B1 G-protein-coupled receptors, which bind peptides of the corticotropin releasing factor family and are key mediators in the stress response. In order to dissect the receptors' binding specificity and enable structural studies, full-le...
Autores principales: | Jappelli, Roberto, Perrin, Marilyn H., Lewis, Kathy A., Vaughan, Joan M., Tzitzilonis, Christos, Rivier, Jean E., Vale, Wylie W., Riek, Roland |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894963/ https://www.ncbi.nlm.nih.gov/pubmed/24465390 http://dx.doi.org/10.1371/journal.pone.0084013 |
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