Acute NMDA Receptor Antagonism Disrupts Synchronization of Action Potential Firing in Rat Prefrontal Cortex

Antagonists of N-methyl-D-aspartate receptors (NMDAR) have psychotomimetic effects in humans and are used to model schizophrenia in animals. We used high-density electrophysiological recordings to assess the effects of acute systemic injection of an NMDAR antagonist (MK-801) on ensemble neural proce...

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Detalles Bibliográficos
Autores principales: Molina, Leonardo A., Skelin, Ivan, Gruber, Aaron J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895008/
https://www.ncbi.nlm.nih.gov/pubmed/24465743
http://dx.doi.org/10.1371/journal.pone.0085842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895008/
https://www.ncbi.nlm.nih.gov/pubmed/24465743
http://dx.doi.org/10.1371/journal.pone.0085842

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