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Isolation of Highly Suppressive CD25+FoxP3+ T Regulatory Cells from G-CSF-Mobilized Donors with Retention of Cytotoxic Anti-Viral CTLs: Application for Multi-Functional Immunotherapy Post Stem Cell Transplantation

Previous studies have demonstrated the effective control of cytomegalovirus (CMV) infections post haematopoietic stem cell transplant through the adoptive transfer of donor derived CMV-specific T cells (CMV-T). Strategies for manufacturing CMV immunotherapies has involved a second leukapheresis or b...

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Detalles Bibliográficos
Autores principales: Samuel, Edward R., Beloki, Lorea, Newton, Katy, Mackinnon, Stephen, Lowdell, Mark W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895016/
https://www.ncbi.nlm.nih.gov/pubmed/24465783
http://dx.doi.org/10.1371/journal.pone.0085911