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Canonical WNT Signaling Inhibits Follicle Stimulating Hormone Mediated Steroidogenesis in Primary Cultures of Rat Granulosa Cells

Beta-catenin (CTNNB1), a key component of wingless-type mouse mammary tumor virus integration site family (WNT) signaling, participates in follicle stimulated hormone-mediated regulation of estrogen (E(2)) production. The purpose of these studies was to determine if CTNNB1’s contribution to FSH-medi...

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Detalles Bibliográficos
Autores principales: Stapp, Andrea D., Gómez, Belinda I., Gifford, Craig A., Hallford, Dennis M., Hernandez Gifford, Jennifer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895028/
https://www.ncbi.nlm.nih.gov/pubmed/24466091
http://dx.doi.org/10.1371/journal.pone.0086432