The Not4 E3 Ligase and CCR4 Deadenylase Play Distinct Roles in Protein Quality Control

Eukaryotic cells control their proteome by regulating protein production and protein clearance. Protein production is determined to a large extent by mRNA levels, whereas protein degradation depends mostly upon the proteasome. Dysfunction of the proteasome leads to the accumulation of non-functional...

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Detalles Bibliográficos
Autores principales: Halter, David, Collart, Martine A., Panasenko, Olesya O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895043/
https://www.ncbi.nlm.nih.gov/pubmed/24465968
http://dx.doi.org/10.1371/journal.pone.0086218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895043/
https://www.ncbi.nlm.nih.gov/pubmed/24465968
http://dx.doi.org/10.1371/journal.pone.0086218

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