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Persistent prelimbic cortex activity contributes to enhanced learned fear expression in females

Anxiety disorders, such as post-traumatic stress, are more prevalent in women and are characterized by impaired inhibition of learned fear and medial prefrontal cortex (mPFC) dysfunction. Here we examined sex differences in fear extinction and mPFC activity in rats. Females showed more learned fear...

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Detalles Bibliográficos
Autores principales: Fenton, Georgina E., Pollard, Amelia K., Halliday, David M., Mason, Rob, Bredy, Timothy W., Stevenson, Carl W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895223/
https://www.ncbi.nlm.nih.gov/pubmed/24429423
http://dx.doi.org/10.1101/lm.033514.113