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Tumor microenvironment–associated modifications of alternative splicing

Pre-mRNA alternative splicing is modified in cancer, but the origin and specificity of these changes remain unclear. Here, we probed ovarian tumors to identify cancer-associated splicing isoforms and define the mechanism by which splicing is modified in cancer cells. Using high-throughput quantitati...

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Detalles Bibliográficos
Autores principales: Brosseau, Jean-Philippe, Lucier, Jean-François, Nwilati, Hanad, Thibault, Philippe, Garneau, Daniel, Gendron, Daniel, Durand, Mathieu, Couture, Sonia, Lapointe, Elvy, Prinos, Panagiotis, Klinck, Roscoe, Perreault, Jean-Pierre, Chabot, Benoit, Abou-Elela, Sherif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895271/
https://www.ncbi.nlm.nih.gov/pubmed/24335142
http://dx.doi.org/10.1261/rna.042168.113