A molecular brake controls the magnitude of long-term potentiation

Overexpression of suprachiasmatic nucleus circadian oscillatory protein (SCOP), a negative ERK regulator, blocks long-term memory encoding. Inhibition of calpain-mediated SCOP degradation also prevents the formation of long-term memory, suggesting rapid SCOP breakdown is necessary for memory encodin...

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Detalles Bibliográficos
Autores principales: Wang, Yubin, Zhu, Guoqi, Briz, Victor, Hsu, Yu-Tien, Bi, Xiaoning, Baudry, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895372/
https://www.ncbi.nlm.nih.gov/pubmed/24394804
http://dx.doi.org/10.1038/ncomms4051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895372/
https://www.ncbi.nlm.nih.gov/pubmed/24394804
http://dx.doi.org/10.1038/ncomms4051

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