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Effect of Hepatitis B Virus X Gene on the Expression Level of p53 Gene using Hep G2 Cell Line

BACKGROUND: The HBV-X (HBX) protein is believed to contribute to the development of HCC. However, the molecular mechanisms involved in HBX- mediated hepatocarcinogenesis remain obscure. In this study, the effect of hepatitis B virus X gene and its protein product HBxAg on expression of p53 gene in H...

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Detalles Bibliográficos
Autores principales: Kordestani, Roghyeh, Mirshafiee, Hamideh, Hosseini, Seyed Masoud, Sharifi, Zohreh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Avicenna Research Institute 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895577/
https://www.ncbi.nlm.nih.gov/pubmed/24523952